| 发明名称 |
2-CHLORO-4-ANILINO-QUINAZOLINE COMPOUNDS INHIBITING PROTEIN TYROSINE KINASES, PHARMACEUTICAL COMPOSITIONS COMPRISING THE SAME, METHOD FOR PRODUCING THE SAME AND TYROSINE KINASE INHIBITION METHOD |
| 摘要 |
<p>The present invention relates to 2-chloro-4-anilino-quinazoline derivatives with EGFR and/or VEGFR-2 protein tyrosine kinase inhibiting activity, to anti-tumour pharmaceutical compositions that comprise said compounds, and to methods for producing the same. The present invention further provides a method for treating solid tumours by inhibition of tyrosine kinases.</p> |
| 申请公布号 |
WO2014113859(A1) |
申请公布日期 |
2014.07.31 |
| 申请号 |
WO2014BR00034 |
申请日期 |
2014.01.24 |
| 申请人 |
UNIVERSIDADE FEDERAL DO RIO DE JANEIRO |
发明人 |
DE LACERDA BARREIRO, ELIEZER JESUS;DE CASTRO BARBOSA, MARIA LETÍCIA;MOREIRA LIMA, LIDIA;LAUFER, STEFAN, ANDREAS;RABELLO DE SANT'ANNA, CARLOS MAURICIO;TESCH, ROBERTA |
| 分类号 |
C07D239/95;A61K31/498;A61P35/00 |
主分类号 |
C07D239/95 |
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