发明名称 |
2-ARYLIMIDAZOLE DERIVATIVES AS PDE10A ENZYME INHIBITORS |
摘要 |
This invention is directed to compounds of formula I having the structure which are PDE10A enzyme inhibitors. The invention provides a pharmaceutical composition comprising a therapeutically effective amount of a compound of the invention and a pharmaceutically acceptable carrier. The present invention also provides processes for the preparation of the compounds of formula I. The present invention further provides a method of treating a subject suffering from a neurodegenerative disorder comprising administering to the subject a therapeutically effective amount of a compound of formula I The present invention also provides a method of treating a subject suffering from a drug addiction comprising administering to the subject a therapeutically effective amount of a compound of formula I. The present invention further provides a method of treating a subject suffering from a psychiatric disorder comprising administering to the subject a therapeutically effective amount of a compound of formula I. |
申请公布号 |
PT2513105(E) |
申请公布日期 |
2014.07.31 |
申请号 |
PT20100797990T |
申请日期 |
2010.12.15 |
申请人 |
H. LUNDBECK A/S |
发明人 |
JAN KEHLER;ASK PÜSCHL;JOHN PAUL KILBURN;MAURO MARIGO;MORTEN LANGGARD;JACOB NIELSEN |
分类号 |
C07D471/04;A61K31/519;A61P25/00;C07D487/04 |
主分类号 |
C07D471/04 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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