发明名称 |
CELL CULTURE MEMBRANE, CELL CULTURE SUBSTRATE, AND METHOD FOR MANUFACTURING CELL CULTURE SUBSTRATE |
摘要 |
Provided is: a cell culture membrane, which is free from materials derived from living organisms, can easily be industrially mass-produced, exhibits superior long-term storage properties and chemical resistance, has excellent cell adhesion properties and long-term culture properties and is capable of replicating a cell adhesion morphology that is similar to that of collagen derived from living organisms and being used for conventional cell cultivation. Also provided are a cell culture substrate, and a method for manufacturing the cell culture substrate. In the present invention, as a cell adhesion layer, a polymer membrane represented by formula (I) is formed on the base of a cell culture substrate so as to have a membrane thickness equal to or greater than 0.2 μm (in the formula, R1 and R2 represent a —(CH2)n—NH2 moiety (n is an integer of 1-10 inclusive.) or H, with at least one of R1 and R2 being a —(CH2)n—NH2 moiety. Moreover, l and m are positive integers expressing polymerization degree).; |
申请公布号 |
US2014212974(A1) |
申请公布日期 |
2014.07.31 |
申请号 |
US201214128089 |
申请日期 |
2012.06.22 |
申请人 |
Yoshimoto Yasuo;Kamimae Kentaro;Tanabe Yuki;Oguni Taku;Inoue Takashi;Mochizuki Tsutomu;Hirama Makoto;Fujii Teruo;Kimura Hiroshi;Tozawa Hideto |
发明人 |
Yoshimoto Yasuo;Kamimae Kentaro;Tanabe Yuki;Oguni Taku;Inoue Takashi;Mochizuki Tsutomu;Hirama Makoto;Fujii Teruo;Kimura Hiroshi;Tozawa Hideto |
分类号 |
C12N5/00;B05D1/00 |
主分类号 |
C12N5/00 |
代理机构 |
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代理人 |
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主权项 |
1. A cell culture membrane comprising:
a polymer membrane that is composed of a structural unit represented by the following formula (I) and formed on a base, with a membrane thickness of 0.2 μm or more. (in the formula, R1 and R2 represent a —(CH2)n—NH2 moiety (n is an integer of 1-10 inclusive.) or H, with at least one of R1 and R2 being a —(CH2)n—NH2 moiety. Moreover, l and m are positive integers expressing polymerization degree.) |
地址 |
Tokyo JP |