发明名称 CELL CULTURE MEMBRANE, CELL CULTURE SUBSTRATE, AND METHOD FOR MANUFACTURING CELL CULTURE SUBSTRATE
摘要 Provided is: a cell culture membrane, which is free from materials derived from living organisms, can easily be industrially mass-produced, exhibits superior long-term storage properties and chemical resistance, has excellent cell adhesion properties and long-term culture properties and is capable of replicating a cell adhesion morphology that is similar to that of collagen derived from living organisms and being used for conventional cell cultivation. Also provided are a cell culture substrate, and a method for manufacturing the cell culture substrate. In the present invention, as a cell adhesion layer, a polymer membrane represented by formula (I) is formed on the base of a cell culture substrate so as to have a membrane thickness equal to or greater than 0.2 μm (in the formula, R1 and R2 represent a —(CH2)n—NH2 moiety (n is an integer of 1-10 inclusive.) or H, with at least one of R1 and R2 being a —(CH2)n—NH2 moiety. Moreover, l and m are positive integers expressing polymerization degree).;
申请公布号 US2014212974(A1) 申请公布日期 2014.07.31
申请号 US201214128089 申请日期 2012.06.22
申请人 Yoshimoto Yasuo;Kamimae Kentaro;Tanabe Yuki;Oguni Taku;Inoue Takashi;Mochizuki Tsutomu;Hirama Makoto;Fujii Teruo;Kimura Hiroshi;Tozawa Hideto 发明人 Yoshimoto Yasuo;Kamimae Kentaro;Tanabe Yuki;Oguni Taku;Inoue Takashi;Mochizuki Tsutomu;Hirama Makoto;Fujii Teruo;Kimura Hiroshi;Tozawa Hideto
分类号 C12N5/00;B05D1/00 主分类号 C12N5/00
代理机构 代理人
主权项 1. A cell culture membrane comprising: a polymer membrane that is composed of a structural unit represented by the following formula (I) and formed on a base, with a membrane thickness of 0.2 μm or more. (in the formula, R1 and R2 represent a —(CH2)n—NH2 moiety (n is an integer of 1-10 inclusive.) or H, with at least one of R1 and R2 being a —(CH2)n—NH2 moiety. Moreover, l and m are positive integers expressing polymerization degree.)
地址 Tokyo JP