| 发明名称 |
Toll-Like Receptor 3 Antagonists |
| 摘要 |
Toll Like Receptor 3 (TLR3) antibody antagonists, polynucleotides encoding TLR3 antibody antagonists or fragments thereof, and methods of making and using the foregoing are disclosed. |
| 申请公布号 |
US2014212426(A1) |
申请公布日期 |
2014.07.31 |
| 申请号 |
US201313751718 |
申请日期 |
2013.01.28 |
| 申请人 |
Cunningham Mark;Feng Yiqing;Heeringa Katharine;Luo Jinquan;Rauchenberger Robert;Rutz Mark;San Mateo Lani;Sarisky Robert;Stojanovic-Susulic Vedrana;Sweet Raymond;Teng Fang;Teplyakov Alexey;Wu Sheng-Jiun |
发明人 |
Cunningham Mark;Feng Yiqing;Heeringa Katharine;Luo Jinquan;Rauchenberger Robert;Rutz Mark;San Mateo Lani;Sarisky Robert;Stojanovic-Susulic Vedrana;Sweet Raymond;Teng Fang;Teplyakov Alexey;Wu Sheng-Jiun |
| 分类号 |
C07K16/28 |
主分类号 |
C07K16/28 |
| 代理机构 |
|
代理人 |
|
| 主权项 |
1) An isolated antibody or fragment thereof that binds toll-like receptor 3 (TLR3), wherein the antibody binds at least one TLR3 amino acid residue selected from the group consisting of residues D116 and K145 of SEQ ID NO: 2. |
| 地址 |
Spring House PA US |
