发明名称 N-METHYLSEROTONIN AND RELATED SUBSTANCES FOR USE IN TREATING / LESSENING THE OCCURRENCE OF HOT FLASHES RELATED TO MENOPAUSE
摘要 Zanthoxylum piperitum (commonly known as Japanese pepper) seeds, including its mature seeds, contain the NMS precursor /V-methylserotonin 5-O-&Bgr;-glucoside ("NMS-glucoside") present in sufficient concentration and are metabolized with sufficient efficiency so as to provide an effective amount of NMS for use in amelioration of menopausal symptoms, including hot flashes/flushes. The Japanese pepper seeds or Japanese pepper seed extracts can also be used to enrich other sources of NMS or NMS precursors in order to provide a nutraceutical or food supplement for controlling hot flashes.
申请公布号 WO2014115113(A1) 申请公布日期 2014.07.31
申请号 WO2014IB58524 申请日期 2014.01.24
申请人 DSM IP ASSETS B.V. 发明人 BUTT, CHRISTOPHER MICHEAL;WEISER, MICHEAL
分类号 A61K36/758;A61P15/12 主分类号 A61K36/758
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