发明名称 GLYCOSYLATION ATRIAL NATRIURETIC PEPTIDE
摘要 The present invention provides a glycosylation atrial natriuretic peptide with extended sustaining properties in blood, and that has cGMP increasing activity. The present invention provides a modified peptide coupled to at least one saccharide directly by a glycoside bond, or coupled to at least one hANP peptide through a linker structure, and also provides a pharmaceutically permissible salt thereof, and a drug or the like containing the modified peptide or salt thereof as an active ingredient.
申请公布号 WO2014115797(A1) 申请公布日期 2014.07.31
申请号 WO2014JP51357 申请日期 2014.01.23
申请人 DAIICHI SANKYO COMPANY,LIMITED 发明人 IWAMOTO, MITSUHIRO;YAMAGUCHI, TAKAHIRO;MORI, YUTAKA;SAITO, KEIJI;HONDA, TAKESHI;NAGAYAMA, TAKAHIRO
分类号 C07K14/58;A61K38/00;A61K47/26;A61K47/34;A61K47/48;A61P1/16;A61P9/00;A61P9/04;A61P9/10;A61P9/12;A61P13/12;A61P35/00;A61P35/04;A61P43/00;C12P21/02 主分类号 C07K14/58
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