Methods of Treatment Using A Pentapeptide Derived From The C-Terminus Of Glucagon-Like Peptide 1 (GLP-1)

摘要

Methods of treating obesity, metabolic syndrome, hepatic and non-hepatic steatosis, and diabetes using a pentapeptide, LVKGRamide, derived from the C-terminus of Glucagon-Like Peptide 1 (GLP-1).

主权项

1. A therapeutic composition comprising an isolated peptide consisting essentially of a sequence:(SEQ ID NO: 3)Leu-Val-(Lys/Arg)-Gly-Arg-Xaa, wherein Xaa can be Gly, Gly-Arg, Gly-Arg-Gly, or absent,and a physiologically acceptable carrier.