| 发明名称 |
TARGETS AND AGENTS FOR THE TREATMENT OF IMPAIRED BONE FRACTURE HEALING |
| 摘要 |
The application teaches a composition comprising one or more pharmaceutical active ingredients selected from the group consisting of interleukin-8 (IL-8 or CXCL8), a functional fragment of IL-8, a functional variant of IL-8, and an agonist of IL-8 receptor, for therapeutic and/orprophylactic interventions in impaired bone fracture healing, such as but not limited to non-union fractures, mal-union fractures, or delayed union fractures. |
| 申请公布号 |
US2014212380(A1) |
申请公布日期 |
2014.07.31 |
| 申请号 |
US201214124165 |
申请日期 |
2012.06.11 |
| 申请人 |
Gangji Valerie;Hauzeur Jean-Philippe;De Seny Dominique;Mathieu Myrielle;Ingels Aude;Rigutto Sabrina;Spruyt Delphine;Bastianelli Enrico;Albarani Valentina;Pesesse Xavier;Malaise Michel |
发明人 |
Gangji Valerie;Hauzeur Jean-Philippe;De Seny Dominique;Mathieu Myrielle;Ingels Aude;Rigutto Sabrina;Spruyt Delphine;Bastianelli Enrico;Albarani Valentina;Pesesse Xavier;Malaise Michel |
| 分类号 |
C07K14/54 |
主分类号 |
C07K14/54 |
| 代理机构 |
|
代理人 |
|
| 主权项 |
1. A method of treating impaired bone fracture healing, the method comprising a step of administering one or more pharmaceutical active ingredients selected from the group consisting of interleukin-8 (IL-8), a functional fragment of IL-8, a functional variant of IL-8, and an agonist of IL-8 receptor. |
| 地址 |
Rhode-Saint-Genese BE |
