| 发明名称 |
SOLID DISPERSION FORMULATION OF AN ANTIVIRAL COMPOUND |
| 摘要 |
Disclosed are solid dispersions comprising ledipasvir, wherein ledipasvir is dispersed within a polymer matrix formed by a pharmaceutically acceptable polymer, and further wherein ledipasvir is substantially amorphous. Also disclosed are pharmaceutical compositions comprising solid dispersion and methods of using the solid dispersion. |
| 申请公布号 |
US2014212487(A1) |
申请公布日期 |
2014.07.31 |
| 申请号 |
US201414168329 |
申请日期 |
2014.01.30 |
| 申请人 |
Gilead Pharmasset LLC |
发明人 |
Mogalian Erik;Oliyai Reza;Stefanidis Dimitrios;Zia Vahid |
| 分类号 |
A61K47/38;A61K47/32;A61K47/48;A61K31/4184 |
主分类号 |
A61K47/38 |
| 代理机构 |
|
代理人 |
|
| 主权项 |
1. A solid dispersion comprising ledipasvir having the formula:wherein ledipasvir is dispersed within a polymer matrix formed by a pharmaceutically acceptable polymer, and further wherein ledipasvir is substantially amorphous. |
| 地址 |
Foster City CA US |
