发明名称 USE OF SATURATED AMINE COMPOUNDS IN PREPARING MEDICINES TO RESIST RADIATION DAMAGE AND PROMOTE REGENERATION AND REPAIR OF RADIATION-DAMAGED TISSUES
摘要 Disclosed in the present invention is new use of saturated amine compounds for use in preparing medicines to resist radiation damage and promoting regeneration and repair of radiation-damaged tissues. Experiments show that the saturated amine compounds can increase the counts of white blood cells (WBC), red blood cells (RBC) and platelets (PLT) in the peripheral blood of radiation-damaged animals, promote multiplication of bone marrow hematopoietic stem/progenitor cells and restoration of the hematopoietic system, and bring favorable reparative effects to the intestinal, hepatic and pulmonary tissues of radiation-damaged mice, thus significantly improving the survival rate of radiation-damaged animals.
申请公布号 WO2014114254(A1) 申请公布日期 2014.07.31
申请号 WO2014CN71281 申请日期 2014.01.23
申请人 BEIJING INSTITUTE OF TRANSFUSION MEDICINE, ACADEMY OF MILITARY MEDICAL SCIENCES 发明人 PEI, XUETAO;LI, YANHUA;WANG, SIHAN;ZHANG, JING;YAO, HAILEI;SHI, WEI;YUE, WEN
分类号 A61K31/13;A61K31/132;A61P17/16;A61P39/00 主分类号 A61K31/13
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