发明名称 |
QUINOLINE AND QUINOXALINE DERIVATIVES AS KINASE INHIBITORS |
摘要 |
<p>A series of quinoline derivatives, substituted by an optionally substituted bicyclic heteroaryl moiety consisting of two fused six-membered aromatic rings attached via an alkylene chain optionally linked to a heteroatom, being selective inhibitors of PI3 kinase enzymes, are accordingly of benefit in medicine, for example in the treatment of inflammatory, autoimmune, cardiovascular, neurodegenerative, metabolic, oncological, nociceptive or ophthalmic conditions.</p> |
申请公布号 |
EP2499129(B1) |
申请公布日期 |
2014.07.30 |
申请号 |
EP20100781864 |
申请日期 |
2010.11.11 |
申请人 |
UCB PHARMA, S.A. |
发明人 |
ALLEN, DANIEL, REES;BÜRLI, ROLAND;HAUGHAN, ALAN, FINDLAY;MATTEUCCI, MIZIO;OWENS, ANDREW, PATE;RAPHY, GILLES;SHARPE, ANDREW |
分类号 |
C07D403/04;A61K31/517;A61P9/00;A61P25/28;A61P29/00;A61P35/00;C07D487/04 |
主分类号 |
C07D403/04 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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