发明名称 |
STEROID ALKALOIDS AND USES THEREOF AS ANTIMICROBIAL AGENTS AGAINST ELECTRON TRANSPORT-DEFICIENT MICROBES AND AS POTENTIATORS FOR ANTIMICROBIAL AGENTS AGAINST PATHOGENIC BACTERIA |
摘要 |
The present invention includes novel compounds based on the tomatidine skeleton as well as composition comprising these compounds alone and in combination with known compounds, which exhibit antimicrobial activity against extracellular or intracellular electron transport-deficient microbes and/or increase the antimicrobial activity of aminoglycoside antibiotics against their targets, and which are useful as antibacterial agents for treatment or prophylaxis of monomicrobiotic or polymicrobic bacterial infections or for the reduction of antibiotic resistance development in animals or in humans, or for use as antiseptics or agents for sterilization or disinfection. |
申请公布号 |
EP2675822(A4) |
申请公布日期 |
2014.07.30 |
申请号 |
EP20120747258 |
申请日期 |
2012.02.15 |
申请人 |
SOCPRA-SCIENCES ET GÉNIE S.E.C. |
发明人 |
MALOUIN, FRANÇOIS;MITCHELL, GABRIEL;BOUARAB, KAMAL;MARSAULT, ERIC;CHAGNON, FÉLIX;BOULANGER, SIMON;GUAY, ISABELLE |
分类号 |
C07J71/00;A61K31/395;A61K31/58;A61K31/7036;A61L2/16;A61P31/00;A61P31/04;C07J53/00;C12Q1/18 |
主分类号 |
C07J71/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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