发明名称 |
Urea and carbamate derivatives of 2-morpholino-1,3,5-triazine as mTOR inhibitors for the treatment of immunological or proliferative diseases |
摘要 |
The invention relates to compounds of formula (I) wherein m, n, R1, T0 and T1 have the meaning as cited in the description and the claims. The compounds are useful as inhibitors of mTOR for the treatment or prophylaxis of mTOR related diseases and disorders. The invention also relates to pharmaceutical compositions including said compounds as well as methods of treating mTOR related diseases. |
申请公布号 |
EP2758379(A1) |
申请公布日期 |
2014.07.30 |
申请号 |
EP20120761738 |
申请日期 |
2012.09.21 |
申请人 |
CELLZOME LIMITED |
发明人 |
LYNCH, ROSEMARY;CANSFIELD, ANDREW DAVID;HARDY, DANIEL PAUL;SUNOSE, MIHIRO;MOREL, ADELINE;CONVERY, LAURA;ADREGO, RITA |
分类号 |
C07D251/22;A61K31/53;A61P35/00;A61P37/02;A61P37/04;A61P37/06;A61P37/08;C07D401/12;C07D407/12;C07D413/04 |
主分类号 |
C07D251/22 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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