CYCLOALKYLNITRILE PYRAZOLE CARBOXAMIDES AS JANUS KINASE INHIBITORS
摘要
The instant invention provides compounds of formula I which are JAK inhibitors, and as such are useful for the treatment of JAK-mediated diseases such as rheumatoid arthritis, asthma, COPD and cancer.
申请公布号
EP2758377(A1)
申请公布日期
2014.07.30
申请号
EP20120833410
申请日期
2012.09.21
申请人
MERCK SHARP & DOHME CORP.
发明人
BRUBAKER, Jason;DINSMORE, Christopher J.;HOFFMAN, Dawn Marie;JUNG, Joon;LIU, Duan;PETERSON, Scott;SIU, Tony;TORRES, Luis E.;ZHANG, Hongjun;WEI, Zhongyong;SHI, Feng