Means and methods for diagnosing and/or treating a subject at risk of developing heart failure

摘要

The present invention relates to an in vitro method for identifying a subject at risk of developing heart failure, comprising: determining the level of biological marker amyloid beta (A4) precursor protein (APP) and/or the level of expression of a gene coding for APP in a biological sample of said subject; comparing the level of said biological marker to a standard level of the same biological marker; wherein an increased level of APP protein and/or an increased APP gene expression is indicative of a risk for developing heart failure.