发明名称 |
PROTONATED HYDROGEN ION-EXCHANGED LAYERED PHYLLOSILICATE MATERIAL FOR USE IN TREATING ATHEROSCLEROSIS |
摘要 |
<p>Layered phyllosilicates are useful for adsorbing and/or binding to cholesterol and, thereby, reducing blood cholesterol in a patient. Accordingly, provided herein is a method of reducing hypercholesteremia in a mammal comprising administering to said mammal a protonated and at least partially exfoliated layered phyllosilicate material alone and in combination with other cholesterol-reducing agents in an amount effective to reduce hypercholesteremia in said mammal. Also provided are methods of treating a cardiovascular disorder associated with atherosclerosis in a mammalian subject comprising administering to the subject a layered phyllosilicate material in an amount effective to reduce atherosclerotic lesion formation in the subject.</p> |
申请公布号 |
EP2257173(B1) |
申请公布日期 |
2014.07.30 |
申请号 |
EP20090716063 |
申请日期 |
2009.02.27 |
申请人 |
AMCOL INTERNATIONAL CORPORATION |
发明人 |
DARLINGTON, JERALD, W., JR. |
分类号 |
A61K33/00;A61K9/14;A61K31/366;A61K31/397;A61K31/575;A61K31/60;A61K33/12;A61P9/10 |
主分类号 |
A61K33/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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