Polymer Carrier

摘要

Compositions and methods for delivering bioactive agents, such as vitamins, hormones, nutrients and drugs, by stabilizing and or solubilizing these agents in a polymer matrix. The carrier polymers can be used in drug delivery and are useful for delivery of small molecules. The carrier polymers also can be used in scaffolds for regenerative medicine.

主权项

1. A combination of a biologically derived polymer for delivering bioactive agents, and a bioactive agent, wherein:
the bioactive agent is a small molecule; the biologically derived polymer is a non-collagenous protein comprising an amino acid sequence selected from the group of sequences consisting of SEQ ID NOS. 3-17; wherein the protein comprises regions composed of hydrophobic residues that form a hydrophobic pore with a threshold radius of 73 Å and a diameter that is 2-6 nm, wherein the bioactive agent is stored within the hydrophobic pore; and the bioactive agent is bound to and encapsulated in the biologically derived polymer, whereby the biologically derived polymer acts as a carrier for the bioactive agent.