Exosomes derived from reticulocytes infected with <i>Plasmodium </i>sp., method for obtaining them and uses thereof

摘要

The present invention belongs to the field of vaccines for the prevention and prophylaxis against malaria, more specifically it relates to exosomes isolated from reticulocytes infected with Plasmodium sp., to methods for obtaining them and to the use thereof for the prevention and prophylaxis against malaria as well as to its use for the discovery and identification of novel Plasmodium antigens. The invention also refers to artificial exosomes comprising Plasmodium sp. antigens. Finally, the invention refers to specific antigens discovered by means of the exosomes obtained from reticulocytes infected with Plasmodium sp.

主权项

1. An isolated peptide comprising the amino acid sequence set forth as SEQ ID NO 1 or a sequence comprising at least 85% sequence identity to the amino acid sequence SEQ ID NO 1.