2-alkynyl-N9-propargyladenine and medicinal use thereof

摘要

In the present invention, a novel 2-alkynyl-N9-propargyladenine represented by formula (I);
wherein R1 represents a halogen atom, a furyl group, or a triazolyl group; R2 and R3 each represents a hydrogen atom or a C1-8 alkyl group, or form a cycloalkyl group by bonding to each other; and X represents a hydrogen atom or a hydroxyl group, or a pharmaceutically acceptable salt thereof, has a stronger and longer-lasting effect as a therapeutic agent for Parkinsonian syndromes.

主权项

1. A compound represented by formula (I): wherein: R1 represents halogen, a furyl group or a triazolyl group; R2 and R3 independently represent hydrogen or an alkyl group having 1 to 8 carbon atoms, or R2 and R3 represent a cycloalkyl group in which R2 and R3 are linked together; and X represents hydrogen or a hydroxyl group,or a pharmaceutically acceptable salt thereof.