Devices and methods for tissue engineering

摘要

A resorbable tissue scaffold fabricated from bioactive glass fiber forms a rigid three-dimensional porous matrix having a bioactive composition. Porosity in the form of interconnected pore space is provided by the space between the bioactive glass fiber in the porous matrix. Strength of the bioresorbable matrix is provided by bioactive glass that fuses and bonds the bioactive glass fiber into the rigid three-dimensional matrix. The resorbable tissue scaffold supports tissue in-growth to provide osteoconductivity as a resorbable tissue scaffold, used for the repair of damaged and/or diseased bone tissue.

主权项

1. A resorbable tissue scaffold comprising:
bioactive glass fiber bonded into a rigid three-dimensional porous matrix; and pore space within the rigid three-dimensional porous matrix by volatile components removed during formation of the three-dimensional porous matrix, wherein the pore space creates a porosity between about 40% and about 85% in the resorbable tissue scaffold.