Treating inflammation with a binding system

摘要

The teachings provided herein generally relate to site-activated binding systems that selectively increase the bioactivity of phenolic compounds at target sites. More particularly, the systems taught here include a phenolic compound bound to a reactive oxygen species, wherein the phenolic compound and the reactive oxygen species react at a target area in the presence of an oxidoreductase enzyme.

主权项

1. A method of treating an inflammation in a subject, comprising:
administering an effective amount of a binding system to a subject having an inflammation, the binding system comprising:
an extract of a plant selected from the group consisting of Chinese gall, Camilla Sinensis, pomegranate, resveratrol, and combinations thereof; and,hydrogen peroxide;wherein,the hydrogen peroxide is combined with the extract at a weight ratio that ranges from about 1:1000 to about 10:1 of the an extract to the hydrogen peroxide; and,the extract comprises a flavanol; wherein the administering inhibits, or ameliorates the symptoms of, the inflammation of the subject.