| 发明名称 | Myosin light chain kinase inhibitor compounds, compositions and related methods of use | ||
| 摘要 | Pyridazinyl compounds, compositions and related methods of use. | ||
| 申请公布号 | US8791116(B2) | 申请公布日期 | 2014.07.29 |
| 申请号 | US201213632920 | 申请日期 | 2012.10.01 |
| 申请人 | Northwestern University | 发明人 | Watterson Daniel Martin;Van Eldik Linda J.;Behanna Heather;Ralay Ranaivo Hantamalala |
| 分类号 | A01N43/58;A61K31/50;C07D487/00 | 主分类号 | A01N43/58 |
| 代理机构 | Reinhart Boerner Van Deuren s.c. | 代理人 | Reinhart Boerner Van Deuren s.c. |
| 主权项 | 1. A compound of a formula wherein R3 is selected from H and alkyl moieties; R4 is selected from H, alkyl, substituted alkyl, phenyl and substituted phenyl moieties; R5 is selected from H and alkyl moieties; R6 is selected from phenyl, substituted phenyl and halo moieties; and R7 is selected from NHC(O)X and C(O)NHX, where X is (CH2)mY, and m is an integer selected from 0 to 3, and Y is selected from pyrrolidinyl, substituted and unsubstituted pyrrolyl, substituted and unsubstituted pyrazolyl, substituted and unsubstituted imidazolyl and substituted and unsubstituted cyclopentyl; and salts thereof. | ||
| 地址 | Evanston IL US | ||