Beta-lactoglobulin-polysaccharide nanoparticles for hydrophobic bioactive compounds

摘要

The present invention provides colloidally stable dispersions of nanoparticles comprising beta-lactoglobulin and a polysaccharide which are transparent when diluted in aqueous media. In particular these colloidally stable dispersions of nanoparticles are useful as delivery vehicles of hydrophobic nutraceuticals and fat-soluble vitamins, for enrichment of food products, especially of transparent beverages and other non-fat or low fat foods and drinks. The present invention further provides methods for the preparation of said colloidally stable dispersions.

主权项

1. A stable colloidal dispersion of nanoparticles comprising an isolated β-lactoglobulin, a polysaccharide and at least one bioactive compound selected from the group consisting of a vitamin, a nutraceutical and a pharmaceutical, wherein the bioactive compound is bound to the β-lactoglobulin, wherein the amount of polysaccharide in the dispersion of nanoparticles is equal to or higher than the amount of β-lactoglobulin, and wherein said dispersion of nanoparticles has an absorbance of less than 0.25 at 600 nm in an aqueous medium, said dispersion being transparent in an aqueous medium.