发明名称 Strains of <i>Helicobacter pylori </i>and uses thereof
摘要 The present invention relates to strains of Helicobacter pylori useful for the delivery of biologically active agents. In particular, the present invention provides an isolated strain of H. pylori having: (a) low pathogenicity; (b) ability to naturally transform; and (c) ability to colonise mouse stomach mucosa without host adaptation.
申请公布号 US8790909(B2) 申请公布日期 2014.07.29
申请号 US201013376377 申请日期 2010.06.03
申请人 Ondek Pty. Ltd. 发明人 Benghezal Mohammed;Fulurija Alma;Lu Wei;Nilsson Hans-Olof;Marshall Barry J.
分类号 C12N1/00 主分类号 C12N1/00
代理机构 Pepper Hamilton LLP 代理人 Pepper Hamilton LLP
主权项 1. An isolated strain of H. pylori comprising the following characteristics: (a) low pathogenicity; (b) ability to naturally transform; and (c) ability to colonize mouse stomach mucosa without host adaptation, wherein said H. pylori is selected from the group consisting of OND737, as deposited in the National Measurement Institute under Accession No. V09/009101; OND738, as deposited in the National Measurement Institute under Accession No. V09/009102; OND739, as deposited in the National Measurement Institute under Accession No. V09/009103; OND248, as deposited in the National Measurement Institute under Accession No. V10/014059; OND256 as deposited in the National Measurement Institute under Accession No. V10/014060 and OND740, as deposited in the National Measurement Institute under Accession No. V09/009104.
地址 Perth AU