| 发明名称 |
MODIFIED LYSINE-MIMETIC COMPOUNDS |
| 摘要 |
Lysine mimetic compounds that are 4-amino-pyrrolidine-2-carboxylic acid analogs having the structure of Formula III, are disclosed. These compounds have useful pharmacological activity such as antiarrhythmic activity and desirable bioavailability properties. Pharmaceutical compositions comprising such compounds and methods of using and making such compounds and compositions are also disclosed. (see formula III) |
| 申请公布号 |
CA2634743(C) |
申请公布日期 |
2014.07.29 |
| 申请号 |
CA20062634743 |
申请日期 |
2006.12.21 |
| 申请人 |
ZEALAND PHARMA A/S;WYETH |
发明人 |
LARSEN, BJARNE DUE;PETERSEN, JORGEN SOBERG;HAUGAN, KETIL JORGEN;BUTERA, JOHN A.;HENNAN, JAMES K.;KERNS, EDWARD H.;PIATNITSKI, EVGUENI LVOVICH |
| 分类号 |
C07C233/81;A61K31/4015;A61K31/4166;A61P9/00;C07D207/16;C07D207/50;C07D233/02 |
主分类号 |
C07C233/81 |
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