FORMULATIONS FOR PREVENTION AND TREATMENT OF BREAST CANCER WITH 4-HYDROXY TAMOXIFEN 4-

摘要

The present invention provides methods for treating breast cancer by administering 4-hydroxy tamoxifen to a patient. It also provides pharmaceutical compositions of 4-hydroxy tamoxifen suitable for percutanous administration. When percutaneously administered to a patient's breasts, 4-hydroxy tamoxifen concentrates locally, and exerts an anti-estrogenic effect. In patients with breast cancer, this effect reduces tumor tissue proliferation.