摘要 |
The present invention refers to biochemistry, namely to new peptide compounds having the ability to selectively block the muscle-type nicotinic acetylcholine receptor. The claimed compounds have common formula (I): X1-X2-X3-Pro-X4-X5-X6, where X1 is chosen within H, Ac-, Palm-; X2 is chosen within Trp, Tyr, His, Phe, Pro; X3 is chosen within Trp, Tyr, His, Phe, Lys, Om, Dbu, Dpr, Arg; X5 is chosen within Trp, Tyr, His, Phe, Pro; X6 is chosen within -OH, -NH2, -OCH3, -OC2H5, -NH-C6H5. The invention can be applied in cosmetics for smoothing mimic and age-related wrinkles. |
申请人 |
LIMITED LIABILITY COMPANY "SYNEURO |
发明人 |
ZHMAK, MAXIM NURGAYANOVICH;UTKIN, YURY NIKOLAEVICH;ANDREEVA, TATYANA VIKTOROVNA;KUDRYAVTSEV, DENIS SERGEEVICH;KRYUKOVA, ELENA VIKTOROVNA;TSETLIN, VIKTOR IONOVICH;KASHEVEROV, IGOR EVGEN`EVICH;STARKOV, VLADISLAV GENNAD`EVICH;SHELUKHINA, IRINA VALER`EVNA |