发明名称 HLA-DR1 RESTRICTIVE TAX SPECIFIC CD4+ T CELL EPITOPE
摘要 PROBLEM TO BE SOLVED: To provide an HTLV-I specific CD4T cell-inducing active peptide having an inducing activity of HTLV-I specific CD4T cells, an HTLV-I specific CTL inductive action enhancer containing the peptide, and an HTLV-I specific immune response-inducing vaccine and a diagnostic agent for immunological function test using them.SOLUTION: There is provided an HTLV-I specific CD4T cell-inducing activity peptide consisting of any of a specific amino acid sequence, an amino acid sequence consisting of 14-30 continuous amino acids in a specific amino acid sequence or an amino acid sequence made by binding the amino acid sequence and an amino acid sequence of an HTLV-I specific CTL-inducing activity peptide, and an amino acid sequence which has an identity of 80% or more to the above amino acid sequence, or in which one to some amino acids are deleted, substituted or added, wherein a peptide consisting of the amino acid sequence has HTLV-I specific CD4T cell-inducing activity.
申请公布号 JP2014133712(A) 申请公布日期 2014.07.24
申请号 JP20130002127 申请日期 2013.01.09
申请人 TOKYO MEDICAL AND DENTAL UNIV 发明人 TAMAI YOTARO;HASEGAWA ATSUHIKO;KANAKI MARI;TANOZAKI RYUJI
分类号 C07K14/47;A61K31/7088;A61K38/00;A61K39/00;A61K48/00;A61P35/02;A61P43/00;C07K7/08;C07K19/00;C12N15/09;G01N33/48 主分类号 C07K14/47
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