ELECTROMAGNETICALLY ACTUATED DROPLET MICROFLUIDIC CHIP AND SYSTEM

摘要

A microfluidic system includes a microfluidic cartridge and an electromagnetic droplet actuator arranged proximate the microfluidic cartridge. The microfluidic cartridge includes a plurality of droplet wells with topological barrier structures between adjacent wells. The topological barrier structures are configured to allow magnetic particles and material attached to the magnetic particles to pass between adjacent wells while confining droplets within respective wells. The electromagnetic droplet actuator includes a plurality of electromagnetic components arranged to provide an electronically selectable magnetic field pattern to actuate movement of a plurality of magnetic particles when contained within at least one droplet in at least one of the plurality of droplet wells.

主权项

1. A microfluidic system, comprising:
a microfluidic cartridge; and an electromagnetic droplet actuator arranged proximate said microfluidic cartridge, wherein said microfluidic cartridge comprises a plurality of droplet wells with topological barrier structures between adjacent wells, wherein said topological barrier structures are configured to allow magnetic particles and material attached to said magnetic particles to pass between adjacent wells while confining droplets within respective wells, and wherein said electromagnetic droplet actuator comprises a plurality of electromagnetic components arranged to provide an electronically selectable magnetic field pattern to actuate movement of a plurality of magnetic particles when contained within at least one droplet in at least one of said plurality of droplet wells.