Method for production of n-butanol from syngas using syntrophic co-cultures of anaerobic microorganisms

摘要

This invention provides methods and systems for the production of butanol. Specifically, the methods and systems of the present invention use syntrophic co-cultures for the production of butanol from syngas.

主权项

1. A method for producing butanol comprising exposing gaseous substrates comprising of a carbon source and an electron source to a syntrophic co-culture comprising: a C1-fixing homoacetogenic microorganism having the enzymes of the Wood Ljungdahl pathway; and a C4-producing butyrate microorganism under anaerobic conditions effective for the syntrophic co-culture to convert the gaseous substrate into butanol,
wherein the carbon source is at least one of carbon monoxide and carbon dioxide and the electron source is at least one of hydrogen and carbon monoxide and wherein the C1-fixing homoacetogenic microorganism is capable of converting the carbon source and the electron source into at least one of ethanol and acetate and wherein the C4-producing butyrate microorganism is a butyrogen capable of converting the ethanol and acetate into n-butyrate.