发明名称 |
METHODS OF USING (+)-1,4-DIHYDRO-7-[(3S,4S)-3-METHOXY-4-(METHYLAMINO)-1-PYRROLIDINYL]-4-OXO-1-(2-THIAZOLYL)-1,8-NAPHTHYRIDINE-3-CARBOXYLIC ACID FOR TREATMENT OF CANCER |
摘要 |
Methods of treating, preventing or managing cancer, including certain leukemias are disclosed. The methods encompass the administration of enantiomerically pure (+)-1,4-dihydro-7-[(3S,4S)-3-methoxy-4-(methylamino)-1-pyrrolidinyl]-4-oxo-1-(2-thiazolyl)-1,8-naphthyridine-3-carboxylic acid. Also provided are methods of treatment using this compound with chemotherapy, radiation therapy, hormonal therapy, biological therapy or immunotherapy. Pharmaceutical compositions and single unit dosage forms suitable for use in the methods are also disclosed. |
申请公布号 |
US2014205680(A1) |
申请公布日期 |
2014.07.24 |
申请号 |
US201314056877 |
申请日期 |
2013.10.17 |
申请人 |
SUNESIS PHARMACEUTICALS, INC. |
发明人 |
Adelman Daniel C.;Silverman Jeffrey A.;Arkin Michelle;Hyde Jennifer;Walker Duncan;Wright Jasmin |
分类号 |
A61K31/4375;A61K45/06 |
主分类号 |
A61K31/4375 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
South San Francisco CA US |