发明名称 |
FIVE-AND-SIX-MEMBERED HETEROCYCLIC COMPOUND, AND PREPARATION METHOD, PHARMACEUTICAL COMPOSITION AND USE THEREOF |
摘要 |
A five-and-six-membered heterocyclic compound as represented by general formula I, pharmaceutically acceptable salt, metabolite, metabolic precursors or drug precursors thereof, preparation method, pharmaceutical composition, and use thereof; the five-and-six-membered heterocyclic compound has activity as a Janus kinase (JAK) inhibitor, and can be used to prepare drugs for treating diseases caused by the abnormal activity of kinase, such as cell proliferation diseases like cancer. |
申请公布号 |
WO2014111037(A1) |
申请公布日期 |
2014.07.24 |
申请号 |
WO2014CN70778 |
申请日期 |
2014.01.17 |
申请人 |
SHANGHAI YUNYI HEALTHCARE MANAGEMENT CO., LTD;CHINA GATEWAY TECHNOLOGY DEVELOPMENT (SHANGHAI) COMPANY LIMITED. |
发明人 |
XU, ZUSHENG;ZHANG, NONG;SUN, QINGRUI;WANG, TINGHAN |
分类号 |
C07D495/00;A61K31/519;A61P35/00;C07D487/04;C07D491/048 |
主分类号 |
C07D495/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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