DIFLUOROCARBENE FROM FLUOROFORM FOR PREPARATION OF DIFLUOROMETHYOXYARENES, DIFLUOROTHIOMETHOXYARENES AND HETEROARENES

摘要

A method for the transformation of hydroxyarenes, hydroxyheteroarenes, thiohydroxyarenes or thiohydroxyheteroarenes involves reaction with fluoroform in the presence of base comprising solution to yield a difluoromethoxyarene, diflurothiomethoxyheteroarene, or diflurothiomethoxyheteroarene. The transformation can be carried out at ambient room pressure or at elevated pressures. The transformation can be carried out at temperatures of 0 to 70 °C.