Cinnamic acid hydroxyamides as inhibitors of histone deacetylase 8

摘要

Described herein are compounds and pharmaceutical compositions containing such compounds, which inhibit the activy of histone deacetylase 8 (HDAC8). Also described herein are methods of using such HDAC8 inhibitors, alone and in combination with other compounds, for treating diseases or conditions that would benefit from inhibition of HDAC8 activity.