METHOD OF TISSUE SEPARATION USING FLUIDIC PULSES TO MINIMIZE TISSUE TRAUMA DURING CATHETER INSERTION

摘要

The method and system disclosed herein uses a pulsatile, dilatory bubble at the tip of a catheter to facilitate tissue separation and ease catheter insertion for, among other applications, delivery of therapeutics to the posterior of the eye while reducing procedure-related trauma. In some implementations, the method is extended to other dilatory and catheter-insertion applications elsewhere in the body. In brief, the disclosure discusses iteratively injecting liquid through a catheter to form a bubble near the distal tip of the catheter. The liquid is withdrawn to create a void, and the catheter is advanced into the void. The process is repeated until the distal tip of the catheter reaches the target location.

主权项

1. A method for inserting a catheter between two layers of tissue, the method including:
inserting a distal tip of a catheter between a first layer of tissue and a second layer of tissue; iteratively, until a target destination is reached;
injecting, through a first lumen defined by the catheter, a liquid to form a bubble having a first volume at the distal tip of the catheter between the first layer of tissue and the second layer of tissue;withdrawing, through the catheter, a portion of the first volume used to form the bubble; andadvancing the distal tip of the catheter further between the first layer of tissue and the second layer of tissue.