ENGINEERING AND OPTIMIZATION OF IMPROVED SYSTEMS, METHODS AND ENZYME COMPOSITIONS FOR SEQUENCE MANIPULATION
摘要
<p>The invention provides for engineering and optimization of systems, methods, and compositions for manipulation of sequences and/or activities of target sequences. Provided are compositions and methods related to components of a CRISPR complex particularly comprising a Cas ortholog enzyme.</p>
申请公布号
WO2014093635(A9)
申请公布日期
2014.07.24
申请号
WO2013US74691
申请日期
2013.12.12
申请人
THE BROAD INSTITUTE, INC.;MASSACHUSETTS INSTITUTE OF TECHNOLOGY;ZHANG, FENG;RAN, FEI;SHALEM, OPHIR
