发明名称 |
VARIABLE DOMAINS OF CAMELID HEAVY-CHAIN ANTIBODIES DIRECTED AGAINST GLIAL FIBRILLARY ACIDIC PROTEINS |
摘要 |
The present invention relates to the use of variable domains of camelid heavy-chain antibodies (VHH domains) directed against an intracellular target and having an isoelectric point of at least 8.5, for targeting said intracellular target or for the preparation of a peptide vector. Particularly, it concerns VHH domains directed against a glial fibrillary acidic protein and uses thereof for preparing therapeutic or diagnostic agents. |
申请公布号 |
US2014206081(A1) |
申请公布日期 |
2014.07.24 |
申请号 |
US201313889668 |
申请日期 |
2013.05.08 |
申请人 |
INSTITUT PASTEUR ;SCIENTIFIQUE CENTRE NATIONAL DE LA RECHERCHE |
发明人 |
Lafaye Pierre;Bourgeois Jean-Pierre;Rougeon Francois |
分类号 |
C12N5/079 |
主分类号 |
C12N5/079 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
US |