PHARMACEUTICAL COMPOSITION AND HEALTH FUNCTIONAL FOOD FOR PREVENTING OR TREATING STEROID-INDUCED DIABETES

摘要

The present invention relates to a pharmaceutical composition and a health functional food for preventing or treating steroid-induced diabetes (SID) and, more specifically, to a pharmaceutical composition and a health functional food for preventing or treating steroid-induced diabetes, which contain as an active ingredient an extract from the culture medium of Ceriporia lacerata. The pharmaceutical composition and health functional food according to the present invention have a protective activity for insulin-secreting INS-1 cells by preventing steroid-mediated proliferation inhibition and apoptosis induction in the insulin-secreting INS-1 cells. Accordingly, the pharmaceutical composition and health functional food according to the present invention prevent steroid-mediated growth inhibition and apoptosis in &bgr;-cells and thus can be developed as active ingredients for a pharmaceutical or functional food composition for protecting or regenerating &bgr;-cells.