摘要 |
Provided herein are Pyrrolopyrimidine Compounds having the following structure: wherein R1, R2, R3, and L are as defined herein, compositions comprising an effective amount of a Pyrrolopyrimidine Compound, and methods for treating or preventing breast cancer, more particularly triple negative breast cancer, comprising administering an effective amount of such Pyrrolopyrimidine Compounds to a subject in need thereof. |
申请人 |
SIGNAL PHARMACEUTICALS, LLC |
发明人 |
CALABRESE, ANDREW ANTONY;JEFFY, BRANDON;ROBINSON, DALE;ZHU, DAN;HUANG, DEHUA;ELSNER, JAN;BOYLAN, JOHN;TEHRANI, LIDA;NAGY, MARK A.;RAHEJA, RAJ KUMAR;ERDMAN, PAUL;NARLA, RAMA K.;HARRIS, ROY L.;TRAN, TAM MINH;RIGGS, JENNIFER;NING, YUHONG;XU, SHUICHAN |