发明名称 |
MONOCLONAL ANTIBODIES THAT BIND TO HGM-CSF AND MEDICAL COMPOSITIONS COMPRISING SAME |
摘要 |
Disclosed herein are anti-hGM-CSF monoclonal antibodies and antigen-binding fragments of such antibodies, with improved neutralizing capacity to hGM-CSF activity. Pharmaceutical compositions comprising such an antibody or antigen-binding fragment are also provided. The present invention is useful for the treatment of various diseases that are associated with aberrant expression of hGM-CSF. |
申请公布号 |
US2014205611(A1) |
申请公布日期 |
2014.07.24 |
申请号 |
US201414166803 |
申请日期 |
2014.01.28 |
申请人 |
Boehringer Ingelheim International GmbH ;Evec Inc. |
发明人 |
Takada Kenzo;Nakajima Kantou;Park John;Kistler Barbara |
分类号 |
C07K16/24 |
主分类号 |
C07K16/24 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
Ingelheim Am Rhein DE |