METHOD FOR TREATING CYSTIC FIBROSIS WITH INHALED DENUFOSOL
摘要
The present invention is directed to a method for treating cystic fibrosis. The method comprises the steps of: identifying a patient suffering from cystic fibrosis, applying about 0.8-3 mL of a solution comprising about 18-65 mg/mL of denufosol into a medication reservoir of an nebulizer to achieve a target loading dose of denufosol of about 25-52 mg denufosol per dosing regimen, nebulizing the solution by passing through holes of an vibrating mesh device equipped with an oscillating membrane in the nebulizer, and delivering an inhaled respiratory dose of 20-33 mg to the lungs of the patient by inhalation within 3-9 minutes.
申请公布号
EP2627336(A4)
申请公布日期
2014.07.23
申请号
EP20110833157
申请日期
2011.10.06
申请人
INSPIRE PHARMACEUTICALS, INC.
发明人
KRISHNAMOORTHY, RAMESH;EVANS, CAROLE M.;BURKE, BRIAN J.;SCHABERG, AMY E.;COADY, THOMAS G.