发明名称 |
ANTI-HER2 VACCINE BASED UPON AAV DERIVED MULTIMERIC STRUCTURES |
摘要 |
The present invention relates to parvovirus mutated structural proteins comprising insertions of mimotopes of a HER2, compositions, multimeric structures, medicaments and vaccines comprising the same, nucleic acids, expression cassettes, constructs, vectors and cells comprising the nucleic acids, methods of preparing the structural proteins and methods of inducing a B-cell response or of treating a HER2-related disease. |
申请公布号 |
EP2755677(A1) |
申请公布日期 |
2014.07.23 |
申请号 |
EP20120758868 |
申请日期 |
2012.09.14 |
申请人 |
MEDIGENE AG;BIOMEDICAL INTERNATIONAL R + D GMBH |
发明人 |
MICHAELIS, UWE;JENSEN-JAROLIM, ERIKA;REHFUESS, CHRISTOPH;WEGHOFER, MARGIT |
分类号 |
A61K39/00;C07K14/005;C07K14/71 |
主分类号 |
A61K39/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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