发明名称 METHOD FOR INHIBITING CELL GROWTH, NUCLEIC ACID MOLECULE HAVING RNA INTERFERENCE EFFECT ON NEK10 VARIANT GENE, AND ANTICANCER AGENT
摘要 The present invention provides a method for inhibiting cell growth, a nucleic acid molecule useful as an anticancer agent, and a method for screening novel anticancer agents. In the present invention, inhibitory effects on expression of NEK10 variant gene or inhibitory effects on activity of NEK10 variant protein are obtained in cells by transfecting cells with a nucleic acid molecule having an RNA interference effect on NEK10 variant gene. The present invention also provides a method for screening anticancer agents by using this inhibitory effect as an indicator.
申请公布号 EP2757152(A1) 申请公布日期 2014.07.23
申请号 EP20120831615 申请日期 2012.08.29
申请人 NIPPON KAYAKU KABUSHIKI KAISHA 发明人 SATO, TAKAMICHI
分类号 C12N15/00;A61K31/713;A61K48/00;A61P35/00;C12N15/09;C12N15/113;C12Q1/02;C12Q1/68;G01N33/15;G01N33/50 主分类号 C12N15/00
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