发明名称 BIARYLDERIVATIVES,THEIR PREPARATION AND THEIR THERAPEUTIC APPLICATION
摘要 The present invention relates to aniline derivatives of formula (I), to their preparation and to their therapeutic application, for example in treating glaucoma: Formula (I), R1a represents H, an halogen, a (C1-C6)alkyl or a CN; R1b represents H, an halogen or a (C1-C6)alkyl; R1c represents H or a (C1-C6)alkyl; R2 represents H, an halogen, an OH, an O—(C1-C6)alkyl or (C1-C6)alkyl; R3 represents H, an halogen, a (C1-C6)alkyl, an OH, an O—(C1-C6)alkyl, a CONH2 or CN; R4 represents H, an halogen or a (C1-C6)alkyl; R5 represents H or F: R7 represents H or F; R8 represents H or F; R9 represents H or (C1-C6)alkyl, or one of its enantiomers.
申请公布号 EP2755944(A2) 申请公布日期 2014.07.23
申请号 EP20120762245 申请日期 2012.09.07
申请人 FOVEA PHARMACEUTICALS 发明人 FEUTRILL, JOHN;LERICHE, CAROLINE;MIDDLEMISS, DAVID
分类号 C07C215/76;A61K31/165;A61P27/06;C07C65/105;C07C65/24;C07C217/84;C07C233/75;C07C255/57;C07C255/58;C07C255/59;C07D295/088 主分类号 C07C215/76
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