发明名称 |
HYDROXAMATE-BASED INHIBITORS OF DEACETYLASES B |
摘要 |
<p>The present teachings relate to compounds of Formula I :
and pharmaceutically acceptable salts, hydrates, esters, and prodrugs thereof, wherein R 1 , R 2 , R 3 , Y, Z, and are as defined herein. The present teachings also provide methods of preparing compounds of Formula I and methods of using compounds of Formula I in treating, inhibiting, or preventing pathologic conditions or disorders mediated wholly or in part by deacetylases.</p> |
申请公布号 |
EP2260020(B1) |
申请公布日期 |
2014.07.23 |
申请号 |
EP20090725624 |
申请日期 |
2009.03.24 |
申请人 |
NOVARTIS AG |
发明人 |
SHULTZ, MICHAEL;CHEN, CHRISTINE, HIU-TUNG;CHO, YOUNG SHIN;JIANG, LEI;FAN, JIANMEI;LIU, GANG;MAJUMDAR, DYUTI;LI, JIANKE |
分类号 |
C07D207/08;A61K31/4025;A61P35/00;C07D401/06;C07D403/06;C07D405/06;C07D413/06;C07D471/04 |
主分类号 |
C07D207/08 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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