| 发明名称 |
Device, method, and system for neural modulation as vaccine adjuvant in a vertebrate subject |
| 摘要 |
A method for enhancing an immune response in a vertebrate subject is described. The method includes providing at least one energy stimulus configured to modulate one or more nervous system components of the vertebrate subject, and administering one or more immunogen to the vertebrate subject, wherein the at least one energy stimulus and the one or more immunogen are provided in a combination and in a temporal sequence sufficient to enhance an immune response in the vertebrate subject. |
| 申请公布号 |
US8788037(B2) |
申请公布日期 |
2014.07.22 |
| 申请号 |
US201213673517 |
申请日期 |
2012.11.09 |
| 申请人 |
The Invention Science Fund I, LLC |
发明人 |
Della Rocca Gregory J.;Dowling Joshua L.;Goodall Eleanor V.;Hyde Roderick A.;Kare Jordin T.;Ishikawa Muriel Y.;Leuthardt Eric C.;Malaska Stephen L.;Myhrvold Nathan P.;Santiago Paul;Stewart Todd J.;Sweeney Elizabeth A.;Tegreene Clarence T.;Wood, Jr. Lowell L.;Wood Victoria Y. H. |
| 分类号 |
A61N1/36 |
主分类号 |
A61N1/36 |
| 代理机构 |
|
代理人 |
|
| 主权项 |
1. A method for eliciting an enhanced immune
response to a neoplasm in a vertebrate subject comprising: providing at least one energy stimulus from one or more transducers, wherein the at least one energy stimulus is configured to modulate one or more nervous system components in a tissue of the vertebrate subject, and administering one or more immunogen to the vertebrate subject, wherein the at least one energy stimulus and the one or more immunogen are configured to provide in a combination and in a temporal sequence sufficient to enhance an immune response to the one or more immunogen in the vertebrate subject. |
| 地址 |
Bellevue WA US |
