System and methods for processing analyte sensor data

摘要

Systems and methods for processing sensor analyte data, including initiating calibration, updating calibration, evaluating clinical acceptability of reference and sensor analyte data, and evaluating the quality of sensor calibration. During initial calibration, the analyte sensor data is evaluated over a period of time to determine stability of the sensor. The sensor may be calibrated using a calibration set of one or more matched sensor and reference analyte data pairs. The calibration may be updated after evaluating the calibration set for best calibration based on inclusion criteria with newly received reference analyte data. Fail-safe mechanisms are provided based on clinical acceptability of reference and analyte data and quality of sensor calibration. Algorithms provide for optimized prospective and retrospective analysis of estimated blood analyte data from an analyte sensor.

主权项

1. A method for evaluating a calibration of an analyte sensor, the method comprising:
receiving sensor data from an analyte sensor, during a time period of continuous analyte sensing of a host, including one or more sensor data points; receiving reference data, during the time period of continuous analyte sensing of the host, including one or more reference data points; providing one or more matched data pairs by matching a reference data point to a substantially time corresponding sensor data point; forming a calibration set including the one or more matched data pairs; evaluating, during the time period of continuous analyte sensing of the host, a clinical acceptability of the one or more matched data pairs, wherein the clinical acceptability is based at least in part on a clinical error grid analysis; and processing the sensor data in response to the clinical acceptability of the one or more matched data pairs meeting a criterion.