发明名称 |
Encapsulated reagents and methods of use |
摘要 |
The present invention contemplates use of encapsulated aqueous and non-aqueous reagents, solutions and solvents and their use in laboratory procedures. These encapsulated aqueous or non-aqueous reagents, solutions and solvents can be completely contained or encapsulated in microcapsules or nanocapsules that can be added to an aqueous or non-aqueous carrier solution or liquid required for medical and research laboratory testing of biological or non-biological specimens. |
申请公布号 |
US8785124(B2) |
申请公布日期 |
2014.07.22 |
申请号 |
US201313944619 |
申请日期 |
2013.07.17 |
申请人 |
|
发明人 |
Angros Lee H. |
分类号 |
C12Q1/68 |
主分类号 |
C12Q1/68 |
代理机构 |
Dunlap Codding, P.C. |
代理人 |
Dunlap Codding, P.C. |
主权项 |
1. A method of treating a biological specimen on an analytic substrate, comprising:
disposing a liquid mixture upon an analytic substrate having a biological specimen disposed thereon and a residual wash buffer with at least one detergent present in the buffer disposed over the biological specimen, the liquid mixture comprising an oil-based carrier solution having dispersed therein a quantity of at least one of a plurality of microcapsules and a plurality of nanocapsules encapsulating at least one of a DNA probe and a RNA probe disposed in at least one detergent containing an aqueous solution; and exposing the analytic substrate and the liquid mixture thereon to a temperature change sufficient to cause the release of the at least one of DNA probe and RNA probe and the detergent containing aqueous solution into the oil-based carrier solution such that at least one of the DNA probe and the RNA probe and the detergent containing aqueous solution separate from the oil-based carrier solution so as to become available to act on or react with the biological specimen and the residual wash buffer. |
地址 |
Bethany OK US |