发明名称 |
Aqueous liquid preparations and light-stabilized aqueous liquid preparations |
摘要 |
An aqueous liquid preparation containing (+)-(S)-4-[4-[(4-chlorophenyl)(2-pyridyl)methoxy]piperidino]butyric acid or a pharmacologically acceptable acid addition salt thereof, which is stabilized with a water-soluble metal chloride, is provided. |
申请公布号 |
US8784789(B2) |
申请公布日期 |
2014.07.22 |
申请号 |
US200310500354 |
申请日期 |
2003.07.30 |
申请人 |
Senju Pharmaceutical Co., Ltd. |
发明人 |
Higashiyama Masayo |
分类号 |
A61K31/4545;A61K47/02;A61K9/00 |
主分类号 |
A61K31/4545 |
代理机构 |
Wenderoth, Lind & Ponack, LLP |
代理人 |
Wenderoth, Lind & Ponack, LLP |
主权项 |
1. An aqueous liquid preparation consisting of, in an aqueous solution, an active ingredient consisting of (+)-(S)-4-[4-[(4-chlorophenyl)(2-pyridyl)methoxy]piperidino]butyric acid or a pharmacologically acceptable acid addition salt thereof; a water-soluble metal chloride in a light-stabilizing effective amount; water; and optionally at least one material selected from the group consisting of a buffer, a preservative, a chelating agent, and a flavor; wherein the metal chloride has a concentration selected from the range of a lower limit concentration of 0.2 w/v % and an upper limit concentration of 1.2 w/v %. |
地址 |
Osaka JP |