发明名称 |
Use of FSH receptor ligands for diagnosis and therapy of cancer |
摘要 |
The present invention relates to diagnostic imaging and in particular to the diagnostic imaging and therapy of cancer by means of compositions which specifically target the FSH Receptor expressed by tumor endothelial cells and circulating blood cells. |
申请公布号 |
US8784776(B2) |
申请公布日期 |
2014.07.22 |
申请号 |
US200912866519 |
申请日期 |
2009.02.18 |
申请人 |
Inserm (Institut National de la Sante et de la Recherche Medicale);Mount Sinai School of Medicine |
发明人 |
Ghinea Nicolae;Radu Aurelian |
分类号 |
A61K39/395;A61K49/00 |
主分类号 |
A61K39/395 |
代理机构 |
Saliwanchik, Lloyd & Eisenschenk |
代理人 |
Saliwanchik, Lloyd & Eisenschenk |
主权项 |
1. A method for imaging vessels associated with a tumor in a patient, the method comprising administering a labeled Vascular Endothelial follicle-stimulating hormone (FSH) receptor (VE-FSHR) ligand to said patient and imaging said patient to detect the in vivo binding of said ligand to a VE-FSHR in vessels associated with the tumor in said patient. |
地址 |
Paris Cedex FR |